Dr. Mateos on Ixazomib-Lenalidomide-Dexamethasone in Relapsed/Refractory Multiple Myeloma

Maria-Victoria Mateos, MD, PhD
Published: Thursday, Jun 30, 2016



Maria-Victoria Mateos, consultant physician, hematology department, Hospital Universitario de Salamanca, MD, PhD, discusses the TOURMALINE-MM1 trial in multiple myeloma.
 
The phase III trial investigated the impact of prior therapy on efficacy and safety of oral ixazomib-lenalidomide-dexamethasone (IRd) compared to placebo plus lenalidomide-dexamethasone in patients with relapsed/refractory multiple myeloma (RRMM).
 
The IRd combination resulted in a significant improvement in progression free survival (PFS) compated to the control arm, says Mateos.
 
The benefit was sustained across different groups of patients regardless of prior lines of therapy.
 


Maria-Victoria Mateos, consultant physician, hematology department, Hospital Universitario de Salamanca, MD, PhD, discusses the TOURMALINE-MM1 trial in multiple myeloma.
 
The phase III trial investigated the impact of prior therapy on efficacy and safety of oral ixazomib-lenalidomide-dexamethasone (IRd) compared to placebo plus lenalidomide-dexamethasone in patients with relapsed/refractory multiple myeloma (RRMM).
 
The IRd combination resulted in a significant improvement in progression free survival (PFS) compated to the control arm, says Mateos.
 
The benefit was sustained across different groups of patients regardless of prior lines of therapy.
 

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