Dr. Osborne on Pertuzumab in HER2+ Breast Cancer

C. Kent Osborne, MD
Published: Tuesday, Apr 25, 2017



C. Kent Osborne, MD, director, Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, discusses pertuzumab (Perjeta) in HER2-positive breast cancer.

The NEOSPHERE study showed that adding pertuzumab to trastuzumab (Herceptin) doubled the complete pathological response rate in the neoadjuvant stetting when it was combined with docetaxel.

Pertuzumab was also used in the APHINITY trial, results of which have not been published, but are indicating that pertuzumab provides some additional benefit in the adjuvant setting, says Osborne.
 


C. Kent Osborne, MD, director, Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, discusses pertuzumab (Perjeta) in HER2-positive breast cancer.

The NEOSPHERE study showed that adding pertuzumab to trastuzumab (Herceptin) doubled the complete pathological response rate in the neoadjuvant stetting when it was combined with docetaxel.

Pertuzumab was also used in the APHINITY trial, results of which have not been published, but are indicating that pertuzumab provides some additional benefit in the adjuvant setting, says Osborne.
 

View Conference Coverage
Online CME Activities
TitleExpiration DateCME Credits
Cancer Summaries and Commentaries™: Update from Chicago: Advances in the Treatment of Breast CancerJul 31, 20181.0
Community Practice Connections™: Medical Crossfire®: Translating Lessons Learned with PARP Inhibition to the Treatment of Breast Cancer—Expert Exchanges on Novel Strategies to Personalize CareAug 29, 20181.5
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