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Dr. Papadimitrakopoulou on Treatment Options for EGFR-Mutant NSCLC

Vassiliki A. Papadimitrakopoulou, MD
Published: Friday, Jun 02, 2017



Vassiliki A. Papadimitrakopoulou, MD, professor, Department of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, discusses treatment options for patients with EGFR-mutant non-small cell lung cancer (NSCLC).

There are multiple options for first-line therapy for patients with EGFR-mutant NSCLC, explains Papadimitrakopoulou. The first-generation EGFR tyrosine kinase inhibitors (TKI’s) are actively being used in the community and academic setting.

Second-line therapy for patients who have developed a resistance to first-generation EGFR TKI’s has been dominated by the FDA approval of osimertinib (Tagrisso), states Papadimitrakopoulou. Osimertinib has become the standard of care for patients whose tumors have developed a T790M mutation.



Vassiliki A. Papadimitrakopoulou, MD, professor, Department of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, discusses treatment options for patients with EGFR-mutant non-small cell lung cancer (NSCLC).

There are multiple options for first-line therapy for patients with EGFR-mutant NSCLC, explains Papadimitrakopoulou. The first-generation EGFR tyrosine kinase inhibitors (TKI’s) are actively being used in the community and academic setting.

Second-line therapy for patients who have developed a resistance to first-generation EGFR TKI’s has been dominated by the FDA approval of osimertinib (Tagrisso), states Papadimitrakopoulou. Osimertinib has become the standard of care for patients whose tumors have developed a T790M mutation.


View Conference Coverage
Online CME Activities
TitleExpiration DateCME Credits
Oncology Briefings™: Updates in Novel Therapeutic Options for Lung Neuroendocrine TumorsMay 31, 20181.0
Community Practice Connections™: Working Group to Optimize Outcomes in EGFR-mutated Lung Cancers: Evolving Concepts for Nurses to Facilitate and Improve Patient CareJun 30, 20181.5
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