Dr. Radich on the Potential of Biosimilars in Oncology

Jerald P. Radich, MD
Published: Monday, Sep 24, 2018



Jerald P. Radich, MD, clinical research division, Fred Hutchinson Cancer Research Center, discusses the potential of biosimilars in oncology.

Biosimilars have a lot of potential in oncology, explains Radich, but one of the concerns about biosimilars is their efficacy in comparison to their originator biologics. Radich notes that it is very unlikely that a biosimilar is going to reach the clinic without having met the standards that are in place for approval.

Nonetheless, it may take a while for people to become familiar and comfortable with the use of biosimilars in oncology, says Radich. In addition to the recent approvals of the bevacizumab (Avastin) biosimilar ABP-215 (bevacizumab-awwb; Mvasi), and the trastuzumab (Herceptin) biosimilar MYL-1401O (Ogivri; trastuzumab-dkst), several biosimilars are in development for the treatment of patients with cancer.

ABP-215 was the first oncologic biosimilar to be approved in the United States. The Amgen and Allergan product was approved for the treatment of adult patients with colorectal, lung, brain, kidney, and cervical cancers.


Jerald P. Radich, MD, clinical research division, Fred Hutchinson Cancer Research Center, discusses the potential of biosimilars in oncology.

Biosimilars have a lot of potential in oncology, explains Radich, but one of the concerns about biosimilars is their efficacy in comparison to their originator biologics. Radich notes that it is very unlikely that a biosimilar is going to reach the clinic without having met the standards that are in place for approval.

Nonetheless, it may take a while for people to become familiar and comfortable with the use of biosimilars in oncology, says Radich. In addition to the recent approvals of the bevacizumab (Avastin) biosimilar ABP-215 (bevacizumab-awwb; Mvasi), and the trastuzumab (Herceptin) biosimilar MYL-1401O (Ogivri; trastuzumab-dkst), several biosimilars are in development for the treatment of patients with cancer.

ABP-215 was the first oncologic biosimilar to be approved in the United States. The Amgen and Allergan product was approved for the treatment of adult patients with colorectal, lung, brain, kidney, and cervical cancers.

View Conference Coverage
Online CME Activities
TitleExpiration DateCME Credits
Advent of Oncology Monoclonal Antibody Biosimilars ‒ A European Perspective OnlineNov 30, 20183.0
Community Practice Connections™: Evaluating the Emerging Role of Biosimilar Agents for the Treatment of Hematologic MalignanciesMar 08, 20193.0
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