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Dr. Rodriguez on Systemic Therapy in Salivary Gland Cancer

Cristina P. Rodriguez, MD
Published: Wednesday, Aug 03, 2016


Cristina P. Rodriguez, MD, hematology oncologist, University of Washington School of Medicine in Seattle, discusses the emerging role of systemic therapy for patients with salivary gland cancers.

These are very rare malignancies that are also biologically diverse with 24 subtypes, Rodriguez explains. The challenge with treating these patients with chemotherapy is that there are not enough data from clinical trials to demonstrate its role.

Despite the lack of evidence, there are other agents that elicit activity in these tumors, including platinum-based therapies—whether alone or in combination. Immune checkpoint inhibitors may also have a role in this field. Use of next-generation sequencing might help identify subtypes that have therapeutic targets, she adds.

Cristina P. Rodriguez, MD, hematology oncologist, University of Washington School of Medicine in Seattle, discusses the emerging role of systemic therapy for patients with salivary gland cancers.

These are very rare malignancies that are also biologically diverse with 24 subtypes, Rodriguez explains. The challenge with treating these patients with chemotherapy is that there are not enough data from clinical trials to demonstrate its role.

Despite the lack of evidence, there are other agents that elicit activity in these tumors, including platinum-based therapies—whether alone or in combination. Immune checkpoint inhibitors may also have a role in this field. Use of next-generation sequencing might help identify subtypes that have therapeutic targets, she adds.

View Conference Coverage
Online CME Activities
TitleExpiration DateCME Credits
Clinical Interchange™: Translating Research to Inform Changing Paradigms: Assessment of Emerging Immuno-Oncology Strategies and Combinations across Lung, Head and Neck, and Bladder CancersOct 31, 20182.0
Community Practice Connections™: Precision Medicine for Community Oncologists: Assessing the Role of Tumor-Testing Technologies in Cancer CareNov 30, 20181.0
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