Dr. Shah Discusses Ongoing Research With CAR T-Cell Therapy

Nirav N. Shah, MD
Published: Thursday, May 02, 2019



Nirav N. Shah, MD, assistant professor, Medical College of Wisconsin, discusses ongoing research with CAR T-cell therapy.

There are many studies evaluating future applications of CAR T cells and other cellular therapies, Shah says. There are armored CAR T cells being studied; these differ from the products currently on the market and may prove to be more effective, says Shah. In addition, ongoing research is looking at dual-targeted CAR T cells as well as sequential CAR T-cell therapy.

Moreover, some institutions are studying the role of a different type of immune effector cell called an NK cell. CAR NK is a construct that researchers hope is on the rise as another potential option for patients who have failed traditional treatments, Shah adds.
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Nirav N. Shah, MD, assistant professor, Medical College of Wisconsin, discusses ongoing research with CAR T-cell therapy.

There are many studies evaluating future applications of CAR T cells and other cellular therapies, Shah says. There are armored CAR T cells being studied; these differ from the products currently on the market and may prove to be more effective, says Shah. In addition, ongoing research is looking at dual-targeted CAR T cells as well as sequential CAR T-cell therapy.

Moreover, some institutions are studying the role of a different type of immune effector cell called an NK cell. CAR NK is a construct that researchers hope is on the rise as another potential option for patients who have failed traditional treatments, Shah adds.

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Medical Crossfire®: How Can We Optimize Outcomes in Head and Neck Cancers with Immunotherapeutic Strategies?Oct 31, 20191.5
The Patient and Provider Connection™: Effective Communication to Optimize the Diagnosis and Management of Irritable Bowel Syndrome and Chronic Idiopathic ConstipationOct 31, 20191.0
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