Examining the HER2 Testing Puzzle: Fresh Research Explores Nagging Questions

Anita T. Shaffer @Shaffer1
Published: Tuesday, Mar 27, 2012
Breast Tumor
In the more than 30 years since the human epidermal growth factor receptor 2 (HER2) gene was first successfully explored, HER2 status in patients with breast cancer has emerged as a durable and effective marker for evaluating tumors and selecting therapies.1



The FDA has approved several methods of assessing whether the gene is promoting tumor growth, and HER2 gene amplification and/or protein overexpression has been variously estimated to be at work in 10% to 34% of invasive breast cancers, with the frequency associated with tumor grade and carcinoma status.1-3
Established agents have proved effective in inhibiting HER2-positive forms of the disease, and now the treatment of such cancers is poised to enter a new era as strategies for dual inhibitors have emerged.

Edith A. Perez, MD

Edith A. Perez, MD

“This should prompt a renovated willingness to try and unveil peculiar aspects of HER2-positive breast cancer that have been apparently overlooked or misinterpreted until now,” he said.

... to read the full story
To Read the Full Story

View Conference Coverage
Online CME Activities
TitleExpiration DateCME Credits
Publication Bottom Border
Border Publication
External Resources

MJH Associates
American Journal of Managed Care
Cure
MD Magazine
Oncology Nursing News
Pharmacy Times
Physicians' Education Resource
Physician's Money Digest
Specialty Pharmacy Times
TargetedOnc
OncLive Resources

Articles
Blogs
Conference Coverage
OncLive TV
Peer Exchange
Publications
Specialties
Web Exclusives


About Us
Advertise
Advisory Board
Careers
Contact Us
Forgot Password
Press Releases
Privacy Policy
Terms & Conditions
 
Intellisphere, LLC
2 Clarke Drive
Suite 100
Cranbury, NJ 08512
P: 609-716-7777
F: 609-939-0221

Copyright OncLive 2006-2019
Intellisphere, LLC. All Rights Reserved.
 
x