Closer Study Required of Immunological Differences Between Sexes

Narjust Duma, MD
Published: Monday, Jan 07, 2019
MayoNarjust Duma, MD
Narjust Duma, MD
Hematology and oncology fellow

Mayo Clinic

Rochester, Minnesota

Strategic Partnership
Study results demonstrate that men and women differ in their immunological responses to foreign and self-antigens. Women have stronger responses to vaccinations and infections than men.1 One potential cause of these immunologic differences is sex hormones: Among women, some differences in immune response are more apparent during puberty or child-bearing years. Furthermore, sex hormones might play a role in regulation of the PD-1/PD-L1 pathway, although this theory is based exclusively on data from animal studies.
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Community Practice Connections™: 2nd Annual School of Nursing Oncology™Sep 28, 20191.5
Medical Crossfire®: Experts Weigh-In on Emerging Immune Checkpoint Inhibitors and Combination Strategies for Advanced NSCLCNov 30, 20191.5
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