Investigators Test Immunotherapy Combo in HCC

Rachel Narozniak
Published: Friday, Aug 02, 2019
Stacey Stein, MD

Stacey Stein, MD

Investigators hope to expand frontline treatment options for patients with hepatocellular carcinoma (HCC) via the phase III IMbrave150 study (NCT03434379), which is exploring the synergistic potential of immunotherapy and the immunomodulatory potential of a VEGF inhibitor in locally advanced, metastatic or unresectable HCC. In IMbrave150, patients are being randomized 2:1 to receive either a doublet of atezolizumab (Tecentriq) and bevacizumab (Avastin) or standard-of-care single-agent sorafenib (Nexavar; Figure).1
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