New Paradigm Is Shaping Up for High-Risk Smoldering Myeloma

Andrew Smith
Published: Tuesday, Feb 12, 2019
E. Manasanch, MD

Elisabet E. Manasanch, MD

The nature of smoldering multiple myeloma (SMM) is such that it can develop very rapidly into multiple myeloma (MM) or take years. However, since the disease was first identified almost 40 years ago by Robert Kyle, MD, and Philip Greipp, MD, observation has remained the standard of care.1 During that time, more than a dozen new treatments have boosted survival times for individuals with MM. Now, researchers have begun trials to investigate whether any of those MM treatments might improve on observation for patients with SMM who are at the highest risk of progression.
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