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Latest from NYU Langone's Perlmutter Cancer Center

In this final episode of OncChats: Leveraging Endoscopic Ultrasound in Pancreatic Cancer, Toufic A. Kachaamy, MD, Madappa Kundranda, MD, PhD, and Tamas A. Gonda, MD, reiterate that the role of endoscopic therapies in pancreatic cancer continues to evolve.

Faith E. Davies, MD, discusses challenges experienced by hematologist-oncologists and specialist nurses when treating patients with multiple myeloma.

In this sixth episode of OncChats: Leveraging Endoscopic Ultrasound in Pancreatic Cancer, Toufic A. Kachaamy, MD, Madappa Kundranda, MD, PhD, and Tamas A. Gonda, MD, briefly discuss pancreatic cancer ablation and immune modulation.

Treating MET Exon 14 NSCLC
ByMartin Dietrich, MD, PhD,Julie R. Brahmer, MD,Antonia Sepulveda, MD, PhD,Joshua K. Sabari, MD,Luis E. Raez, MD The focus turns to therapeutic strategies for treating MET exon 14 non–small cell lung cancer.

Approach to Treating Patients with NSCLC and RET Fusions
ByMartin Dietrich, MD, PhD,Julie R. Brahmer, MD,Antonia Sepulveda, MD, PhD,Joshua K. Sabari, MD,Luis E. Raez, MD Experts on non–small cell lung cancer share their approaches to treating patients who have RET fusions and review updates on selpercatinib and pralsetinib.

In this fifth episode of OncChats: Leveraging Endoscopic Ultrasound in Pancreatic Cancer, Toufic A. Kachaamy, MD, Madappa Kundranda, MD, PhD, and Tamas A. Gonda, MD, underscore the need for additional research evaluating the role of radiofrequency ablation and other approaches in pancreatic cancer, and avenues that are ripe for further exploration.

Treatment of NTRK Fusions in NSCLC
ByMartin Dietrich, MD, PhD,Julie R. Brahmer, MD,Antonia Sepulveda, MD, PhD,Joshua K. Sabari, MD,Luis E. Raez, MD Julie R. Brahmer, MD, and Joshua K. Sabari, MD, review recent data on entrectinib and larotrectinib for the treatment of patients with NSCLC with NTRK fusions.

Choosing Between ALK Inhibitors in the Treatment of NSCLC
ByMartin Dietrich, MD, PhD,Julie R. Brahmer, MD,Antonia Sepulveda, MD, PhD,Joshua K. Sabari, MD,Luis E. Raez, MD The expert panel discusses factors that influence treatment decisions when choosing appropriate therapy for patients with ALK-rearranged NSCLC.

Holistic and Multidisciplinary Approaches to Multiple Myeloma Management
ByFaith E. Davies, MD, NYU Langone's Perlmutter Cancer Center,Beth M. Faiman, PhD, MS, APN-BC, BMTCN, AOCN, FAAN, FAPO,Joseph Mikhael, MD, Translational Genomics Research Institute,Katie Joyner, Myeloma Patients Europe Closing out their program on multiple myeloma, expert panelists consider the role of holistic and multidisciplinary care when managing patients within the current paradigm.

Impact of Clinical Trials on the Management of Multiple Myeloma
ByFaith E. Davies, MD, NYU Langone's Perlmutter Cancer Center,Beth M. Faiman, PhD, MS, APN-BC, BMTCN, AOCN, FAAN, FAPO,Joseph Mikhael, MD, Translational Genomics Research Institute,Katie Joyner, Myeloma Patients Europe Continuing its discussion on clinical trials in multiple myeloma, the panel emphasizes the impact that data may have on the real-world treatment landscape.

Bhavana Pothuri, MD, discusses the use of antibody-drug conjugates in patients with ovarian cancer and AEs to be aware of when treating patients with these therapies.

Emerging Treatment Options for Patients with NSCLC with ALK Rearrangements
ByMartin Dietrich, MD, PhD,Julie R. Brahmer, MD,Antonia Sepulveda, MD, PhD,Joshua K. Sabari, MD,Luis E. Raez, MD Experts on non–small cell lung cancer discuss recent data on brigatinib and lorlatinib for the treatment of patients with ALK rearrangements.

Is There a Role for Immunotherapy in Patients with KRAS G12C-Mutant NSCLC and STK11 or KEAP1 Co-Mutations?
ByMartin Dietrich, MD, PhD,Julie R. Brahmer, MD,Antonia Sepulveda, MD, PhD,Joshua K. Sabari, MD,Luis E. Raez, MD Luis Raez, MD, offers insights on how co-mutations in STK11 or KEAP1 impact the use of immunotherapies in KRAS G12C–mutant non–small cell lung cancer.

Bhavana Pothuri, MD, discusses treatment considerations for patients in tough-to-treat subgroups of ovarian cancer based on currently available data.

Importance of Clinical Trial Enrollment in Multiple Myeloma
ByFaith E. Davies, MD, NYU Langone's Perlmutter Cancer Center,Beth M. Faiman, PhD, MS, APN-BC, BMTCN, AOCN, FAAN, FAPO,Joseph Mikhael, MD, Translational Genomics Research Institute,Katie Joyner, Myeloma Patients Europe Key opinion leaders in multiple myeloma management elucidate the value of clinical trials and share enthusiasm for improving enrollment when possible.

Multiple Myeloma: Regulatory Aspects of Treatment Development and Approval
ByFaith E. Davies, MD, NYU Langone's Perlmutter Cancer Center,Beth M. Faiman, PhD, MS, APN-BC, BMTCN, AOCN, FAAN, FAPO,Joseph Mikhael, MD, Translational Genomics Research Institute,Katie Joyner, Myeloma Patients Europe A focused discussion on the regulatory aspects of drug testing and approval, globally, with respect to the setting of multiple myeloma management.

In this third episode of OncChats: Leveraging Endoscopic Ultrasound in Pancreatic Cancer, Toufic A. Kachaamy, MD, Madappa Kundranda, MD, PhD, and Tamas A. Gonda, MD, share how they would best utilize genetic testing results obtained from endoscopic ultrasound–guided biopsies in pancreatic ductal adenocarcinomas.

Adagrasib for Patients with KRAS G12C–Mutant NSCLC
ByMartin Dietrich, MD, PhD,Julie R. Brahmer, MD,Antonia Sepulveda, MD, PhD,Joshua K. Sabari, MD,Luis E. Raez, MD Joshua K. Sabari, MD, discusses adagrasib as a treatment of patients with NSCLC with KRAS G12C mutations, and provides insight on treating patients who have progressed on prior KRAS G12C inhibitors.

Sotorasib in the Treatment of KRAS G12C–Mutant NSCLC
ByMartin Dietrich, MD, PhD,Julie R. Brahmer, MD,Antonia Sepulveda, MD, PhD,Joshua K. Sabari, MD,Luis E. Raez, MD Expert panelists review the CodeBreaK trials focused on sotorasib in the treatment of patients with KRAS G12C-mutant non–small cell lung cancer.

Educating Patients on Treatment Options for Multiple Myeloma
ByFaith E. Davies, MD, NYU Langone's Perlmutter Cancer Center,Beth M. Faiman, PhD, MS, APN-BC, BMTCN, AOCN, FAAN, FAPO,Joseph Mikhael, MD, Translational Genomics Research Institute,Katie Joyner, Myeloma Patients Europe Expert panelists consider best methods in educating patients on their options for therapy following a diagnosis of multiple myeloma.

Treatment for Newly Diagnosed Multiple Myeloma: Addressing Disparities in Care
ByFaith E. Davies, MD, NYU Langone's Perlmutter Cancer Center,Beth M. Faiman, PhD, MS, APN-BC, BMTCN, AOCN, FAAN, FAPO,Joseph Mikhael, MD, Translational Genomics Research Institute,Katie Joyner, Myeloma Patients Europe Comprehensive insight to disparities that may impact a patient’s access to therapy for multiple myeloma and how these may be overcome.

Bhavana Pothuri, MD, discusses the promise of the phase 3 NRG-GY018 and RUBY trials in patients with endometrial cancer.

In this second episode of OncChats: Leveraging Endoscopic Ultrasound in Pancreatic Cancer, Toufic A. Kachaamy, MD, Madappa Kundranda, MD, PhD, and Tamas A. Gonda, MD, discuss the techniques used such as endoscopic ultrasound–guided biopsies to collect adequate tissue to perform genomic analyses in pancreatic cancer, and the likelihood for finding actionable mutations in this population.

NSCLC With Uncommon EGFR Mutations: First-Generation EGFR TKIs and Role of Immunotherapy
ByMartin Dietrich, MD, PhD,Julie R. Brahmer, MD,Antonia Sepulveda, MD, PhD,Joshua K. Sabari, MD,Luis E. Raez, MD Shared insight on the use of first-generation EGFR tyrosine kinase inhibitors and the role of immunotherapy in treating patients with NSCLC with uncommon EGFR mutations.

Choosing Treatments for Patients with NSCLC with Uncommon EGFR Mutations
ByMartin Dietrich, MD, PhD,Julie R. Brahmer, MD,Antonia Sepulveda, MD, PhD,Joshua K. Sabari, MD,Luis E. Raez, MD Julie R. Brahmer, MD, discusses treatment considerations when choosing between afatinib and osimertinib in patients with NSCLC with rare EGFR mutations.

Treatment Considerations for Patients with Newly Diagnosed Multiple Myeloma
ByFaith E. Davies, MD, NYU Langone's Perlmutter Cancer Center,Beth M. Faiman, PhD, MS, APN-BC, BMTCN, AOCN, FAAN, FAPO,Joseph Mikhael, MD, Translational Genomics Research Institute,Katie Joyner, Myeloma Patients Europe Panelists share a brief discussion on the current treatment armamentarium available to patients with newly diagnosed multiple myeloma.

Role of Diagnostic Testing in Patients with Multiple Myeloma
ByFaith E. Davies, MD, NYU Langone's Perlmutter Cancer Center,Beth M. Faiman, PhD, MS, APN-BC, BMTCN, AOCN, FAAN, FAPO,Joseph Mikhael, MD, Translational Genomics Research Institute,Katie Joyner, Myeloma Patients Europe Experts in multiple myeloma management consider essential tests that aid in the diagnosis and treatment of newly presenting patients.

In this first episode of OncChats: Leveraging Endoscopic Ultrasound in Pancreatic Cancer, Toufic A. Kachaamy, MD, Madappa Kundranda, MD, PhD, and Tamas A. Gonda, MD, discuss how endoscopic ultrasound has changed the diagnosis of pancreatic cancer and how it may also be utilized to guide personalized treatment in nonmetastatic adenocarcinomas.

Treatment Options for Patients with NSCLC with EGFR Mutations
ByMartin Dietrich, MD, PhD,Julie R. Brahmer, MD,Antonia Sepulveda, MD, PhD,Joshua K. Sabari, MD,Luis E. Raez, MD Key opinion leaders on non–small cell lung cancer review treatment options for patients with EGFR mutations.

Strategies to Improve Biomarker Testing in NSCLC
ByMartin Dietrich, MD, PhD,Julie R. Brahmer, MD,Antonia Sepulveda, MD, PhD,Joshua K. Sabari, MD,Luis E. Raez, MD Experts on non–small cell lung cancer discuss strategies to improve molecular testing and opportunities for community physicians to reach out to expert oncologists for clinical insights.