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Myelodysplastic neoplasms (MDS; also known as Myelodysplastic Syndromes), and acute myeloid leukemia (AML) are two related but distinct disease entities requiring differential treatment approaches. Watch this video to find out more on the biological, morphological, and clinical differences between the two diseases, and why patient-centric, tailored treatment approaches are important to manage patients with either MDS or AML.

Researcher and clinician, Dr. Francis Worden, reflects on advancements in the treatment of patients with radioactive iodine-refractory differentiated thyroid cancer (RAI-R DTC) and the value of real-world data to provide insights from clinical practice

Exploring Tumor Treating Fields Therapy

THIS ARTICLE IS SPONSORED BY NOVOCURE®. This article includes expert insights from Moshe Giladi, PhD; and Narasimha Kumar Karanam, PhD, BCMAS. Giladi, Novocure’s Chief Science Officer, oversees Novocure’s preclinical research organization and manages external research partnerships and Novocure’s biostatistics and data management teams. Karanam is Novocure’s Medical Science Liaison and has researched the mechanisms of action underlying tumor treating fields therapy.

PAOLA-1: A Review of Progression-Free Survival and 5-Year Follow-up Overall Survival Analysis: Exploratory Post-Hoc Analysis by Clinical Risk of Relapse

Thomas J. Herzog, MD, examines the PAOLA-1 trial results, focusing on the primary endpoint of progression-free survival (PFS) and key secondary endpoint of overall survival for olaparib in combination with bevacizumab for the treatment of advanced ovarian cancer. He discusses the 5-year overall survival data in relation to the PFS data and reviews the safety profile of the combination therapy with over 5 years of median follow-up. Dr. Herzog also considers the impact of these data on clinical decision-making and patient counseling from the perspective of a practicing gynecologic oncologist.

Many people living with diffuse large B-cell lymphoma (DLBCL) continue to experience significant treatment challenges. Genmab and AbbVie discuss the current DLBCL treatment landscape and an effort as part of a collaboration between the two companies for people diagnosed with relapsed or refractory DLBCL.