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Opinion|Videos|July 22, 2024

Clinical Perspectives on Managing ILD Related to T-DXd

Author(s)Joyce A. O'Shaughnessy, MD, Melinda L. Telli, MD, Aditya Bardia, MD, MPH, FASCO

Breast cancer specialists discuss adverse events associated with T-DXd, focusing on monitoring for interstitial lung disease (ILD) and the role of re-challenging patients with T-DXd after resolution of grade 1 ILD.

Episodes in this series

A panel of 5 experts on breast cancer

EP. 1 Challenges in Diagnosing HER2+ Breast Cancer

A panel of 5 experts on breast cancer

EP. 2 Neoadjuvant Treatment Options in HER2+ Early Breast Cancer

A panel of 5 experts on breast cancer

EP. 3 Preoperative Monitoring and Surgical Options for HER2+ Patients

A panel of 5 experts on breast cancer

EP. 4 Clinical Impact of Subcutaneous Fixed-Dose Pertuzumab – trastuzumab-hyaluronidase in HER2+ Breast Cancer

A panel of 5 experts on breast cancer

EP. 5 Standard-of-Care Regimens for First-Line Treatment of HER2+ mBC

A panel of 5 experts on breast cancer

EP. 6 Ongoing Clinical Trials in HER2+ Metastatic Breast Cancer

A panel of 5 experts on breast cancer

EP. 7 Impact of DESTINY-Breast09 and Other Trials on Clinical Practice and Patient Subsets

A panel of 5 experts on breast cancer

EP. 8 Defining HER2 Low and HER2 Ultra-Low: Diagnostic Challenges

A panel of 5 experts on breast cancer

EP. 9 Overview of DESTINY-Breast06

A panel of 5 experts on breast cancer

EP. 10 Clinical Perspectives on Managing ILD Related to T-DXd

A panel of 5 experts on breast cancer

EP. 11 Clinical Considerations and Subsequent Therapies or Sequencing in HER2-Low/HER2+ mBC

A panel of 5 experts on breast cancer

EP. 12 Unmet Needs and Future Direction in HER2+ Breast Cancer

Video content above is prompted by the following questions:

What has your clinical experience been monitoring for T-DXd-related interstitial lung disease (ILD)?
What do you think about the recent data presented about re-challenging patients with T-DXd after resolution of Grade 1 ILD?

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