Commentary|Podcasts|February 13, 2026

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  • Navigating TKI Selection in Chronic Myeloid Leukemia and Acute Lymphoblastic Leukemia
  • Volume 1
  • Issue 1

Comprehensive Ph+ ALL Paradigm Knowledge Informs Frontline Ponatinib Use: With Nicholas Short, MD

Fact checked by: Riley Kandel, Ashling Wahner

Nicholas Short, MD, discusses TKIs like ponatinib and combining them with other treatments for ALL.

Welcome to OncLive On Air®! I’m your host today, Riley Kandel.

OncLive On Air is a podcast from OncLive®, which provides oncology professionals with the resources and information they need to provide the best patient care. In both digital and print formats, OncLive covers every angle of oncology practice, from new technology to treatment advances to important regulatory decisions.

In today’s episode, we spoke with Nicholas Short, MD. Dr Short is an associate professor in the Department of Leukemia of the Division of Cancer Medicine at the University of Texas MD Anderson Cancer Center in Houston.

In our exclusive interview, Dr Short discussed evolving factors at play for the treatment of patients with Philadelphia chromosome (Ph)–positive acute lymphoblastic leukemia (ALL). He also noted how the TKI ponatinib (Iclusig) stacks up against other TKIs for Ph-positive ALL, in addition to evolving approaches that incorporate treatments like blinatumomab (Blincyto).

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