Opinion|Videos|April 21, 2025
ctDNA Biomarkers in INTRIGUE: Understanding Resistance Patterns
Experts discuss the key insights from the follow-up exploratory analysis of the INTRIGUE trial investigating circulating DNA (ctDNA) biomarkers and how mutation-specific findings may influence molecular testing before selecting a second-line agent, with practical implications for implementing a more personalized approach in clinical practice.
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Video content above is prompted by the following:
- A follow-up exploratory analysis of the
INTRIGUE trial investigated ctDNA biomarkers to better understand resistance patterns. Could you discuss the key insights from this analysis? How might these mutation-specific findings change our approach to molecular testing before selecting a second-line agent, and what are the practical implications for implementing this more personalized approach in clinical practice?
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