
The FDA approved camizestrant plus a CDK4/6 inhibitor for hormone receptor–positive, HER2-negative metastatic breast cancer that acquires an ESR1 mutation.
Dr. Mark G. Kris from Memorial Sloan-Kettering cancer center Explains How Gene Signatures are Used
Mark G. Kris, MD, chief of the Thoracic Oncology Service at Memorial Sloan-Kettering Cancer Center, explains the gene signature process which involves testing for the expression of multiple genes and associating the overexpression of these genes with a clinical outcome. He describes gene signatures as a risk stratification system that arranges patients according to their gene signatures.






