Video

Dr. Lyou on Sequencing Apalutamide in Prostate Cancer

Yung Lyou, MD, PhD, discusses optimal sequencing with apalutamide in prostate cancer.

Yung Lyou, MD, PhD, assistant clinical professor, Department of Medical Oncology and Therapeutics Research, City of Hope, discusses optimal sequencing with apalutamide (Erleada) in prostate cancer.

In recent years, many options have become available for the first-line treatment of men with prostate cancer, says Lyou. However, these options have made treatment sequencing more challenging, Lyou explains.

Apalutamide is currently FDA approved to treat men with metastatic castration-sensitive prostate cancer (mCSPC), as well as nonmetastatic castration-resistant prostate cancer (mCRPC), says Lyou. As such, using apalutamide as frontline treatment for patients with castration-sensitive disease leaves the greatest number of treatment options available for patients who progress to metastatic castration-resistant prostate cancer (mCRPC), says Lyou. In mCRPC, apalutamide is not FDA approved and treatment options include docetaxel, abiraterone acetate (Zytiga) plus prednisone, or enzalutamide (Xtandi), concludes Lyou.

Newsletter

Stay up to date on the most recent and practice-changing oncology data

Latest CME

View All
Tumor Board: Expert Insights on Managing Classical 𝘌𝘎𝘍𝘙 Mutations, 𝘌𝘎𝘍𝘙 Exon 20 Insertions, and Atypical 𝘌𝘎𝘍𝘙 Mutations in Metastatic NSCLC
Video

Tumor Board: Expert Insights on Managing Classical 𝘌𝘎𝘍𝘙 Mutations, 𝘌𝘎𝘍𝘙 Exon 20 Insertions, and Atypical 𝘌𝘎𝘍𝘙 Mutations in Metastatic NSCLC

Jun 6th 2025 - Jul 12th 2025

online-activity
Medical Crossfire®: Expert Perspectives on Targeting c-Met Overexpression and 𝘔𝘌𝘛 Genomic Alterations in NSCLC – Unveiling the Complexities of 𝘔𝘌𝘛 Dysregulation
Video

Medical Crossfire®: Expert Perspectives on Targeting c-Met Overexpression and 𝘔𝘌𝘛 Genomic Alterations in NSCLC – Unveiling the Complexities of 𝘔𝘌𝘛 Dysregulation

Jun 6th 2025 - Jul 12th 2025

online-activity
Evolving Treatment Strategies in Pancreatic Cancer: Current Standards, Emerging Targets, and the Role of Molecular Testing
Video

Evolving Treatment Strategies in Pancreatic Cancer: Current Standards, Emerging Targets, and the Role of Molecular Testing

Jun 5th 2025 - Jul 12th 2025

online-activity