Video

Dr. Oh on the Management of Hormone-Sensitive Prostate Cancer

Author(s):

William Oh, MD, chief, Division of Hematology and Medical Oncology, professor of medicine and urology, Mount Sinai School of Medicine, discusses the management of patients with hormone-sensitive prostate cancer.

William Oh, MD, chief, Division of Hematology and Medical Oncology, professor of medicine and urology, Mount Sinai School of Medicine, discusses the management of patients with hormone-sensitive prostate cancer.

One of the biggest developments for the treatment of patients with advanced prostate cancer has been the management of metastatic hormone-sensitive prostate cancer, says Oh. The CHAARTED trial compared androgen deprivation therapy (ADT) versus ADT plus 6 cycles of docetaxel. This study favored the early use of chemotherapy, while the STAMPEDE trial further confirmed those findings.

The LATITUDE trial investigated ADT plus or minus abiraterone (Zytiga) and showed a comparable benefit of up to 2 to 3 years of abiraterone plus prednisone in the treatment of hormone-sensitive prostate cancer.

Related Videos
Albert Grinshpun, MD, MSc, head, Breast Oncology Service, Shaare Zedek Medical Center
Erica L. Mayer, MD, MPH, director, clinical research, Dana-Farber Cancer Institute; associate professor, medicine, Harvard Medical School
Mariya Rozenblit, MD, assistant professor, medicine (medical oncology), Yale School of Medicine
Maxwell Lloyd, MD, clinical fellow, medicine, Department of Medicine, Beth Israel Deaconess Medical Center
Tracy George, MD
Elias Jabbour, MD
Bently P. Doonan, MD
Eytan M. Stein, MD
Azka Ali, MD, medical oncologist, Cleveland Clinic Taussig Cancer Institute
Hope S. Rugo, MD, FASCO, Winterhof Family Endowed Professor in Breast Cancer, professor, Department of Medicine (Hematology/Oncology), director, Breast Oncology and Clinical Trials Education; medical director, Cancer Infusion Services; the University of California San Francisco Helen Diller Family Comprehensive Cancer Center