Dr. Vogelzang Discusses the Cabozantinib Trial Design

Nicholas J. Vogelzang, MD, head of the Genitourinary Cancer Section at the Comprehensive Cancer Centers of Nevada discusses the 9 arm trial design for cabozantinib (XL184) in multiple disease types. Explaining that after 12 weeks of treatment the enrolled patients received scans and blood tests. If they benefited after 12 weeks they were allowed to stay on the drug. If they were stable they could either continue or discontinue using the drug. If the cancer was shown to be growing at anytime throughout the trial or if there was undue toxicity the patients were made to discontinue the trial.