Dr. von Minckwitz on the Safety Profile of the APHINITY Trial for HER2+ Breast Cancer

Gunter von Minckwitz, MD, PhD, president of the German Breast Group in Neu-Isenburg, Germany, discusses the safety profile of the phase III APHINITY trial for patients with HER2-positive breast cancer.

There has been a safety analysis of the APHINITY trial that focused on the impact on the cardiac toxicity, which was shown to be very low, explains von Minckwitz.

The most significant grade 3 side effect that was experienced was diarrhea, states von Minckwitz. This was confined to the chemotherapy period of the trial.