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Commentary|Videos|May 6, 2024

Efficacy With NRG1-Directed Agents in NSCLC

Author(s)Ross Camidge, MD, PhD

D. Ross Camidge, MD, PhD, of University of Colorado Health Lung Cancer Clinic – Anschutz Medical Campus, discusses clinical efficacy with agents targeted for NRG1-fusion–positive non–small cell lung cancer.

Episodes in this series

D. Ross Camidge, MD, PhD

EP. 1 Prevalence of NRG1 Fusions in Lung Cancer

D. Ross Camidge, MD, PhD

EP. 2 Differences Between DNA and RNA Testing for NRG1

D. Ross Camidge, MD, PhD

EP. 3 Standard Treatments for NRG1 Fusion+ NSCLC

D. Ross Camidge, MD, PhD

EP. 4 Ongoing Research Efforts Targeting NRG1 in Lung Cancer

D. Ross Camidge, MD, PhD

EP. 5 Efficacy With NRG1-Directed Agents in NSCLC

E. Gabriela Chiorean, MD

EP. 6 Prognosis, Rarity of NRG1+ Pancreatic Cancer

E. Gabriela Chiorean, MD

EP. 7 Choosing RNA Over DNA Testing for NRG1 Fusions in Pancreatic Cancer

E. Gabriela Chiorean, MD

EP. 8 Standard Treatment Regimens for NRG1+ Pancreatic Cancer

E. Gabriela Chiorean, MD

EP. 9 Poised Potential With Zenocutuzumab in NRG1+ Pancreatic Cancer

Haley M. Hill, PA-C, discusses current approaches and treatment challenges in NRG1-positive non–small cell lung cancer and pancreatic cancer.

EP. 10 Current Approaches and Treatment Challenges in NRG1+ NSCLC and Pancreatic Cancer

Haley M. Hill, PA-C, discusses DNA vs RNA sequencing for genetic testing in non–small cell lung cancer and pancreatic cancer.

EP. 11 DNA vs RNA Sequencing in NSCLC and Pancreatic Cancer

Haley M. Hill, PA-C, discusses how physician assistants aid in treatment planning for NRG1-positive non–small cell lung cancer and pancreatic cancer.

EP. 12 A Physician Assistant's Perspective: Treatment Planning in NRG1+ NSCLC and Pancreatic Cancer

Haley M. Hill, PA-C, discusses preliminary data for zenocutuzumab in NRG1 fusion–positive non–small cell lung cancer and pancreatic cancer.

EP. 13 The Potential Role for Zenocutuzumab in NRG1+ NSCLC and Pancreatic Cancer

Haley M. Hill, PA-C, discusses the role of multidisciplinary management in NRG1-positive non–small cell lung cancer and pancreatic cancer.

EP. 14 Using a Multidisciplinary Treatment Approach in NRG1+ NSCLC and Pancreatic Cancer

Mary B. Beasley, MD, discusses the prevalence of NRG1 fusions in non–small cell lung cancer and pancreatic cancer.

EP. 15 Harnessing the Ability to Target NRG1 Fusions in NSCLC, Pancreatic Cancer

Mary B. Beasley, MD, discusses the role of RNA and other testing considerations for detecting NRG1 and other fusions in solid tumors.

EP. 16 The Role of RNA in Detecting NRG1 and Other Fusions in Solid Tumors

Mary B. Beasley, MD, discusses the role of pathologists in molecular testing in non–small cell lung cancer and pancreatic cancer.

EP. 17 The Pathologist’s Role in Molecular Testing in NSCLC, Pancreatic Cancer

Mary B. Beasley, MD, discusses the multidisciplinary management of NRG1 fusion–positive non–small cell lung cancer and pancreatic cancer.

EP. 18 Using a Multidisciplinary Approach in NRG1+ NSCLC, Pancreatic Cancer

Mary B. Beasley, MD, discusses molecular testing challenges in non–small cell lung cancer and pancreatic cancer.

EP. 19 Overcoming Challenges With Molecular Testing in NSCLC, Other Solid Tumors

NRG1 Fusions in Lung Cancer | Image Credit: © catalin – stock.adobe.com

EP. 20 NRG1 Fusions Emerge as New Target of Interest in Lung, Pancreatic Cancers

Editor's Note: The correct dosage administration of zenocutuzumab is every 2 weeks.

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