October 28th, 2026Sac-TMT Plus Pembrolizumab Improves PFS in PD-L1–Negative Nonsquamous NSCLCSac-TMT plus pembrolizumab prolonged PFS over chemoimmunotherapy in PD-L1–negative nonsquamous lung cancer.Read more
October 26th, 2026Adjuvant Pembrolizumab Sustains DFS Benefit in Resected NSCLCAdjuvant pembrolizumab continued to extend DFS in resected stage IB to IIIA NSCLC, though OS did not differ from placebo.Read more
October 26th, 2026Extended DeLLphi-304 Follow-Up Confirms Durable Survival Benefit With Tarlatamab in Previously Treated SCLCLonger DeLLphi-304 follow-up showed sustained OS, PFS, and response durability with tarlatamab in second-line small cell lung cancer.Read more
October 26th, 2026Iza-Bren Improves PFS vs Platinum Chemo in EGFR-Mutated NSCLC After Third-Generation TKIIzalontamab brengitecan improved progression-free survival vs chemotherapy in EGFR-mutated lung cancer after a third-generation EGFR inhibitor.Read more
October 26th, 2026Savolitinib Combo Extends PFS in Frontline EGFR-Mutated NSCLC and MET OverexpressionFrontline savolitinib plus osimertinib improved progression-free survival vs osimertinib alone in EGFR-mutated, MET-overexpressing lung cancer.Read more
October 26th, 2026FDA Grants Breakthrough Therapy Designation to Enzomenib in R/R KMT2A-Rearranged Acute LeukemiaThe FDA granted breakthrough therapy designation to enzomenib for relapsed/refractory acute leukemia with a KMT2A rearrangement.Read more
October 25th, 2026SAFFRON Data Reveal New Global SOC in EGFR+ NSCLC With MET Overexpression and/or Amplification After OsimertinibIn SAFFRON, the oral EGFR/MET inhibitor pairing extended survival over platinum/pemetrexed in MET-driven lung cancer that progressed on osimertinib.Read more
October 24th, 2026LK101 Plus Tislelizumab Elicits Responses in Advanced NSCLCAdding LK101 to tislelizumab-based first-line maintenance yielded early antitumor activity and signs of immune activation in advanced NSCLC.Read more