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Opinion|Videos|December 9, 2025

Exploring Percutaneous Hepatic Perfusion in Metastatic Uveal Melanoma

Author(s)Prof. Andrea Forschner (DO), Dr. Shaheer Ahmad Khan (MD)

Prof. Andrea Forschner (DO), and Dr. Shaheer Ahmad Khan (MD), discuss the use of percutaneous hepatic perfusion in metastatic uveal melanoma.

Episodes in this series

2 experts are featured in this series.

EP. 1 Future Research Directions in Metastatic Uveal Melanoma

2 experts are featured in this series.

EP. 2 Current Treatment Standards in Metastatic Uveal Melanoma

2 experts are featured in this series.

EP. 3 Exploring Percutaneous Hepatic Perfusion in Metastatic Uveal Melanoma

2 experts are featured in this series.

EP. 4 CHOPIN Trial: Percutaneous Hepatic Perfusion Plus Nivolumab/Ipilimumab in Metastatic Uveal Melanoma

2 experts are featured in this series.

EP. 5 Exploring Potential Implications of CHOPIN Trial Data in Metastatic Uveal Melanoma

2 experts are featured in this series.

EP. 6 Other Strategies Incorporating Percutaneous Hepatic Perfusion in Metastatic Uveal Melanoma

2 experts are featured in this series.

EP. 7 Highlighting Other Uveal Melanoma Data From ESMO 2025 and Beyond

Prof.Andrea Forschner (DO), and Dr. Shaheer Ahmad Khan (MD), discuss the rationale behind percutaneous hepatic perfusion (PHP) as a regional therapy designed to control liver-dominant disease in patients with metastatic uveal melanoma. They outline how PHP delivers high-dose chemotherapy directly to the liver with systemic exposure mitigation, offering a potential therapeutic advantage for selected patients. They also comment on procedural considerations and evolving clinical data that support its use.

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