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Opinion|Videos|December 16, 2025

Exploring Potential Implications of CHOPIN Trial Data in Metastatic Uveal Melanoma

Author(s)Prof. Andrea Forschner (DO), Dr. Shaheer Ahmad Khan (MD)

Prof. Andrea Forschner (DO), and Dr. Shaheer Ahmad Khan (MD), discuss the potential clinical implications of the CHOPIN trial in metastatic uveal melanoma.

Episodes in this series

2 experts are featured in this series.

EP. 1 Future Research Directions in Metastatic Uveal Melanoma

2 experts are featured in this series.

EP. 2 Current Treatment Standards in Metastatic Uveal Melanoma

2 experts are featured in this series.

EP. 3 Exploring Percutaneous Hepatic Perfusion in Metastatic Uveal Melanoma

2 experts are featured in this series.

EP. 4 CHOPIN Trial: Percutaneous Hepatic Perfusion Plus Nivolumab/Ipilimumab in Metastatic Uveal Melanoma

2 experts are featured in this series.

EP. 5 Exploring Potential Implications of CHOPIN Trial Data in Metastatic Uveal Melanoma

2 experts are featured in this series.

EP. 6 Other Strategies Incorporating Percutaneous Hepatic Perfusion in Metastatic Uveal Melanoma

2 experts are featured in this series.

EP. 7 Highlighting Other Uveal Melanoma Data From ESMO 2025 and Beyond

Prof.Andrea Forschner (DO), and Dr. Shaheer Ahmad Khan (MD), explore the clinical implications of data from the phase 2 CHOPIN trial (NCT04283890) and how the findings may influence treatment sequencing or combination strategies in metastatic uveal melanoma. They discuss how improved hepatic control may translate into meaningful survival outcomes and potentially reshape management algorithms. Forschner and Khan explain which patient populations may be best suited for this combined liver-directed and immunotherapy approach.

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