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Opinion|Videos|July 29, 2024

Future Directions and Unmet Needs in HR+ Breast Cancer

Author(s)Virginia G. Kaklamani, MD, DSc, Heather McArthur, MD, MPH

The key opinion leaders discuss the current unmet needs in the management of HR+/HER2- metastatic breast cancer and explore potential future directions and strategies that may lead to improved patient outcomes.

Episodes in this series

2 KOLs are featured in this program.

EP. 1 Prevalence and Testing Strategies for ESR1

2 KOLs are featured in this program.

EP. 2 Evolution of Testing Strategies for ESR1

2 KOLs are featured in this program.

EP. 3 Dynamics of ESR1 Alterations and Serial Liquid Biopsies

2 KOLs are featured in this program.

EP. 4 Case Presentation 1: PIK3CA Mutation With ESR1 Mutations

2 KOLs are featured in this program.

EP. 5 EMERALD Study Design and Results for Elacestrant

2 KOLs are featured in this program.

EP. 6 Evolving Best Practices for ESR1 Testing

2 KOLs are featured in this program.

EP. 7 Case Presentation 2: Co-mutations in ESR1 and PIK3CA

2 KOLs are featured in this program.

EP. 8 PIK3CA Mutations and Delivering PI3K Inhibitors

2 KOLs are featured in this program.

EP. 9 PostMONARCH: Dissecting Data on Sequential CDK 4/6 Inhibitors

2 KOLs are featured in this program.

EP. 10 Combinations and Treatment Sequence Strategies in Breast Cancer

2 KOLs are featured in this program.

EP. 11 Future Directions and Unmet Needs in HR+ Breast Cancer

2 KOLs are featured in this program.

EP. 12 Looking Ahead: Expert Future Perspectives in HR+ Breast Cancer

Looking ahead, what are the key remaining unmet needs and future directions to improve outcomes for HR+/HER2- mBC patients with ESR1 and other mutations driving endocrine resistance?
What novel targets and therapeutic strategies are being explored preclinically and in early trials?

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