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Opinion|Videos|January 20, 2025

In-House Comprehensive Genomic Profiling: Expert Insight Into Balancing Benefits and Challenges

Author(s)Vivek Subbiah, MD, Lucio N. Gordan, MD

Panelists discuss how in-house comprehensive genomic profiling (CGP) testing offers key benefits like reduced turnaround times, direct control over processes, and immediate access to testing resources. However, significant challenges include substantial initial capital investment, the need for specialized staff recruitment and retention, and ongoing equipment maintenance requirements. Health care facilities must carefully weigh these trade-offs, considering their patient volume, existing infrastructure, and financial capabilities before implementing in-house CGP services.

Episodes in this series

2 experts are featured in this series.

EP. 1 Key Considerations When Ordering Biomarker Testing

2 experts are featured in this series.

EP. 2 The Importance of Broad Biomarker Testing: Uncovering Actionable Targets Across Tumor Types

2 experts are featured in this series.

EP. 3 When to Choose Narrow Panel Testing Over Comprehensive Testing in Biomarker Analysis

2 experts are featured in this series.

EP. 4 Centralized vs Decentralized Biomarker Testing: Workflow, Control, and Collaboration Insights

2 experts are featured in this series.

EP. 5 In-House Comprehensive Genomic Profiling: Expert Insight Into Balancing Benefits and Challenges

2 experts are featured in this series.

EP. 6 Implementing In-House Biomarker Testing: Rationale and Key Considerations

2 experts are featured in this series.

EP. 7 Optimizing In-House Testing: Enhancing Efficiency for Timely Results and Treatment Decisions

2 experts are featured in this series.

EP. 8 Enhancing Multidisciplinary Coordination and Treatment Planning Through In-House Testing

2 experts are featured in this series.

EP. 9 Impact of In-House Testing on Improved Cancer Care: Timely Decisions and Enhanced Treatment Accuracy

2 experts are featured in this series.

EP. 10 Decentralization of Biomarker Testing: Expanding Access to Targeted Therapies and Clinical Trials in Underserved Populations

2 experts are featured in this series.

EP. 11 Mitigating Socioeconomic Disparities Through Decentralized Testing: Overcoming Barriers to Access and Equity

2 experts are featured in this series.

EP. 12 Key Takeaways and Future Perspectives for In-House Biomarker Testing

Video series above is prompted by the following:

What are the advantages and disadvantages of using an in-house CGP test?
Discuss potential advantages (eg, faster turnaround time, better control, and direct access to testing resources).
Discuss potential limitations (eg, upfront costs, staffing challenges/needs, and maintaining advanced equipment).

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