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Opinion|Videos|November 4, 2024

Insights from ARTEMIS-001

Author(s)Melissa L. Johnson, MD, Wade T. Iams, MD, Ticiana A. Leal, MD

Panelists discuss how preliminary results from the pPhase 3 ARTEMIS-001 study indicate that iIfinatamab dDeruxtecan, a B7-H3 antibody-drug conjugate, demonstrates promising antitumor activity in relapsed small cell lung cancer, with a notable partial response rate and manageable safety profile among treated patients.

Episodes in this series

EP. 1 Current Landscape of First-Line Treatment for Limited-Stage SCLC: Diagnostic Workup & Multidisciplinary Approaches

EP. 1 Current Landscape of First-Line Treatment for Limited-Stage SCLC: Diagnostic Workup & Multidisciplinary Approaches

EP. 2 Surgical and Radiotherapy Choices in Limited-Stage SCLC

EP. 2 Surgical and Radiotherapy Choices in Limited-Stage SCLC

EP. 3 Durvalumab in LS-SCLC: Exploring Phase 3 ADRIATIC Trial Outcomes and Implications

EP. 3 Durvalumab in LS-SCLC: Exploring Phase 3 ADRIATIC Trial Outcomes and Implications

EP. 4 Immunotherapy in Limited-Stage SCLC

EP. 4 Immunotherapy in Limited-Stage SCLC

EP. 5 Defining Platinum Sensitivity in SCLC

EP. 5 Defining Platinum Sensitivity in SCLC

EP. 6 Changing Standard of Care: Potential of Tarlatamab in SCLC Treatment

EP. 6 Changing Standard of Care: Potential of Tarlatamab in SCLC Treatment

EP. 7 Adverse Event Management: CRS and ICANS with Tarlatamab

EP. 7 Adverse Event Management: CRS and ICANS with Tarlatamab

EP. 8 Tarlatamab in Combination Therapy: Future Potential for SCLC

EP. 8 Tarlatamab in Combination Therapy: Future Potential for SCLC

EP. 9 Ifinatamab Deruxtecan and B7-H3 in SCLC

EP. 9 Ifinatamab Deruxtecan and B7-H3 in SCLC

EP. 10 Comparing Treatment Schedules: Ifinatamab Deruxtecan vs Amrubicin, Topotecan, and Lurbinectedin in SCLC

EP. 10 Comparing Treatment Schedules: Ifinatamab Deruxtecan vs Amrubicin, Topotecan, and Lurbinectedin in SCLC

EP. 11 Insights from ARTEMIS-001

EP. 11 Insights from ARTEMIS-001

EP. 12 Targeted Therapies and Biomarkers for SCLC: What’s Next on the Horizon

EP. 12 Targeted Therapies and Biomarkers for SCLC: What’s Next on the Horizon

Video content above is prompted by the following:

Dr Iams: Please provide your insights on outcomes from the ongoing Phase I ARTEMIS-001[study into which 11 of 53 (20.75%) patients with small cell lung cancer were enrolled.

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