
Opinion|Videos|August 30, 2023
R/R B-ALL: Key Efficacy Outcomes From the Updated Analysis of the ZUMA-3 Trial
Author(s)Jae Park, MD
Jae Park, MD, reviews updated data from the ZUMA-3 trial on the use of the CAR T-cell therapy brexucabtagene autoleucel (brexu-cel) for relapsed/refractory B-cell acute lymphoblastic leukemia, noting high remission rates, management of side effects like cytokine release syndrome, and post-CAR-T consolidation, including transplant.
Advertisement
Episodes in this series

Advertisement
Related to this article

Bexobrutideg produced responses across lines of therapy in chronic lymphocytic leukemia/small lymphocytic lymphoma.

The FDA set a target action date of June 29, 2027, for bezuclastinib's NDA in advanced systemic mastocytosis, backed by APEX trial data.

The phase 3 ECHO trial confirmed a durable progression-free survival benefit with frontline acalabrutinib-based therapy in mantle cell lymphoma.

Daraxonrasib plus gemcitabine and nab-paclitaxel received FDA breakthrough therapy designation for treatment-naive metastatic pancreatic adenocarcinoma.

Alexandra Leary, MD, PhD, discusses TEDOVA's design, the safety profile of OSE2101, and implications for maintenance in ovarian cancer.
Advertisement
Advertisement
Trending on OncLive
1
Dr Drilon on the ARROS-1 Trial Data With Zidesamtinib in ROS1+ NSCLC
2
Dr Rotow on DESTINY-Lung04 Outcomes at WCLC 2026
3
RC148 Plus Chemotherapy in Frontline NSCLC: A Q&A With Yuanyuan Zhao, MD
4
Dr Drilon on How the ARROS-1 Trial May Affect the Current Paradigm in ROS1+ NSCLC
5



