Rugo Summarizes Developments With Ribociclib and ADCs in HR-Positive Breast Cancer

In Partnership With:

Dr Rugo discusses overall survival in the TROPiCS-02 trial, post-progression treatments after ribociclib and endocrine therapy in the MONALEESA-2, MONALEESA-3, and MONALEESA-7 studies, and what the AMALEE trial indicates about optimal doses of ribociclib in hormone receptor–positive breast cancer.

Welcome to OncLive On Air®! I’m your host today, Ashling Wahner.

OncLive On Air® is a podcast from OncLive®, which provides oncology professionals with the resources and information they need to provide the best patient care. In both digital and print formats, OncLive® covers every angle of oncology practice, from new technology to treatment advances to important regulatory decisions.

In today’s episode, sponsored by Novartis, we had the pleasure of speaking with Hope S. Rugo, MD, FASCO, on updates in hormone receptor (HR)–positive breast cancer presented at the 2022 San Antonio Breast Cancer Symposium. Dr Rugo is a professor of medicine in the Division of Hematology and Oncology and the director of Breast Oncology and Clinical Trials Education at the University of California San Francisco Helen Diller Family Comprehensive Cancer Center.

In our exclusive interview, Dr Rugo discussed the findings from the second interim analysis of overall survival in the phase 3 TROPiCS-02 trial (NCT03901339), the implications of post-progression treatments after ribociclib (Kisqali) and endocrine therapy in the phase 3 MONALEESA-2 (NCT01958021), MONALEESA-3 (NCT02422615), and MONALEESA-7 (NCT02278120) studies, and what the phase 2 AMALEE trial (NCT03822468) indicates about optimal starting doses of first-line ribociclib in the HR-positive population.


That’s all we have for today! Thank you for listening to this episode of OncLive On Air®, sponsored by Novartis. Check back on Mondays and Thursdays for exclusive interviews with leading experts in the oncology field.

For more updates in oncology, be sure to visit and sign up for our e-newsletters.

OncLive® is also on social media. On Twitter, follow us at @OncLive and @OncLiveSOSS. On Facebook, like us at OncLive and OncLive State of the Science Summit and follow our OncLive page on LinkedIn.

If you liked today’s episode of OncLive On Air®, please consider subscribing to our podcast on Apple Podcasts, Spotify, Google Podcasts, Amazon Music, and many of your other favorite podcast platforms,* so you get a notification every time a new episode is posted. While you are there, please take a moment to rate us!

Thanks again for listening to OncLive On Air®.

*OncLive On Air® is available on: Apple Podcasts, Google Podcasts, Spotify, Amazon Music, Audacy, CastBox, Deezer, iHeart, JioSaavn, Listen Notes, Player FM, Podcast Addict, Podchaser, RadioPublic, and TuneIn.

Related Videos
Related Content