Utilizing the RSClin Tool to Inform Breast Cancer Treatment Decisions in the Practice Setting

Tools for Result Interpretation

Main Discussion Topics:

• Use of the RSClin tool to individualize risk assessment beyond recurrence score alone
• Integration of clinical-pathological features with genomic information
• Communication approaches with patients about risk and benefit

Key Points for Physicians:

• The RSClin tool combines recurrence score with clinical-pathological data for more precise estimates of recurrence risk and chemotherapy benefit.
• The tool offers multiple visualization options to facilitate patient understanding.
• Physicians should adapt their communication approach based on patient information needs.

Notable Insights:

• Patients often want to know their individual prognosis rather than population-based outcomes.
• Some patients prefer detailed statistical information whereas others simply want clinician recommendations.

Clinical Significance: Tools such as RSClin enhance the clinical utility of genomic testing by providing more individualized risk estimates that can be communicated to patients in ways that match their information preferences.