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Cell-Free DNA Sequencing Could Help Early Detection of Lung Cancer

Brandon Scalea
Published: Thursday, Sep 27, 2018

Geoffrey R.
Oxnard, MD

Geoffrey R. Oxnard, MD
Early-stage lung cancers are detectable in cell-free DNA (cfDNA) using a genome-wide sequencing approach, according to findings of The Circulating Cancer Genome Atlas (CCGA) study.

The study enrolled 12,292 patients, of which 70% with cancer and 30% without. Two initial cohorts were created with a training set (1733 clinically evaluable samples, 127 positive for lung cancer) and a test set (n = 980 clinically evaluable samples, 47 positive for lung cancer).
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