Toni K. Choueiri, MD
Over the last decade, there have been several breakthroughs made in the treatment of patients with renal cell carcinoma (RCC), as checkpoint inhibitors, targeted agents, and combination regimens received approvals from the FDA. Although the outlook is bright for patients, said Toni K. Choueiri, MD, refining what is now a complex treatment paradigm will be challenging.
For example, in the pivotal CheckMate-214 trial, the frontline combination of the checkpoint inhibitors nivolumab (Opdivo) and ipilimumab (Yervoy) demonstrated a clear survival advantage over sunitinib (Sutent) in patients with previously untreated RCC.
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