Yi Long Wu, MD
Crizotinib (Xalkori) induced a nearly 72% overall response rate and a median progression-free survival of almost 16 months in a single-arm phase II trial of 127 patients with ROS1
-positive advanced non–small cell lung cancer (NSCLC).
Overall, 10 patients (7.9%) experienced a grade 5 AE, though none were related to crizotinib.
Wu YL, Yang JCH, Kim DW, et al. Phase II study of crizotinib in East Asian patients with ROS1-positive advanced non–small-cell lung cancer [published online March 29, 2018]. J Clin Oncol. doi: 10.1200/JCO.2017.75.5587.
... to read the full story