Nancy Y. Lee, MD
Investigators are aiming to measure the impact of immunotherapy as an addition to standard chemotherapy plus radiation therapy in patients with locally advanced squamous cell carcinoma of the head and neck in the phase III JAVELIN HEAD AND NECK 100 trial.
, lead study author Nancy Y. Lee, MD, vice chair of the Department of Radiation Oncology at Memorial Sloan Kettering Cancer Center, discussed the ongoing JAVELIN HEAD AND NECK 100 trial and the overall impact of immunotherapy for patients with head and neck cancer.
OncLive: Please provide an overview of this trial.
The trial is for HPV-negative, locally advanced head and neck cancer, but it is also for very advanced HPV-positive head and neck cancer. These are very advanced patients. It is a randomized phase III trial of 640 patients comparing standard of care, which is high-dose cisplatin and fractionary radiation of 70 Gy, versus standard of care plus avelumab.
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