The FDA has accepted a supplemental new drug application (sNDA) for review for avatrombopag (Doptelet) as a treatment for patients with chronic immune thrombocytopenia (ITP) who have had an inadequate response to prior treatment, according to Dova Pharmaceuticals, the developer of the second-generation, oral thrombopoietin receptor agonist.1
Avatrombopag was initially approved by the FDA as a treatment for thrombocytopenia in adults with chronic liver disease who are scheduled to undergo a medical or dental procedure.
- Dova Pharmaceuticals, Inc. Dova Pharmaceuticals announces FDA acceptance of supplemental new drug application for DOPTELET (avatrombopag) for the treatment of chronic immune thrombocytopenia (ITP). Published November 5, 2018. https://bit.ly/2D5WejX. Accessed November 8, 2018.
- Jurczak W, Chonjnowski K, Mayer J, et al. Phase 3 randomization study of avatrombopag, a novel thrombopoietin receptor agonist for the treatment of chronic immune thrombocytopenia [published online September 7, 2018]. Br J Haematol. doi: 10.1111/bjh.15573.
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