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Finasteride Safe and Effective in Prostate Cancer Prevention

Caroline Seymour
Published: Thursday, Feb 14, 2019

Ian Thompson, Jr, MD

Ian Thompson, Jr, MD

The 5α-reductase inhibitor finasteride (Proscar), an agent commonly used to treat lower urinary tract problems and baldness in men, was found to be safe and effective in reducing the risk of prostate cancer, according to the final analysis of the Prostate Cancer Prevention Trial (PCPT) published in the New England Journal of Medicine.1



  1. Goodman PJ, Tangen CM, Darke AK, et al. Long-term effects of finasteride on prostate cancer mortality. N Engl J Med. 2019;380(4):393-394. doi: 10.1056/NEJMc1809961.
  2. Thompson IM, Goodman PJ, Tangen CM, et al. The influence of finasteride on the development of prostate cancer. N Engl J Med. 2003;349(3):215-224. doi: 10.1056/NEJMoa030660.
  3. Thompson IM, Goodman PJ, Tangen CM, et al. Long-term survival of participants in the prostate cancer prevention trial. N Engl J Med. 2013;369(7):603-610. doi: 10.1056/NEJMoa1215932.

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