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Frontline Nivolumab Misses OS Endpoint in Unresectable HCC

Gina Columbus @ginacolumbusonc
Published: Monday, Jun 24, 2019

Bruno Sangro, MD

Bruno Sangro, MD
Nivolumab (Opdivo) did not achieve statistical significance for improved overall survival (OS) compared with sorafenib (Nexavar) as a frontline therapy for patients with unresectable hepatocellular carcinoma (HCC) as per a prespecified analysis, missing the primary endpoint of the phase III CheckMate-459 trial (NCT02576509).
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