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Ibrutinib Combo Falls Short in Pancreatic Cancer

Gina Columbus @ginacolumbusonc
Published: Tuesday, Jan 22, 2019

Danelle James, MD, MAS

Danelle James, MD, MAS

The frontline combination of ibrutinib (Imbruvica) and nab-paclitaxel (Abraxane)/gemcitabine did not show a statistically significant benefit in progression-free or overall survival (OS) versus placebo plus nab-paclitaxel/gemcitabine in patients with metastatic pancreatic cancer, according to topline findings of the phase III RESOLVE (PCYC-1137) trial.1

 

References

  1. AbbVie Provides Update on Phase 3 Study of Ibrutinib (IMBRUVICA®) in Metastatic Pancreatic Cancer. AbbVie. Published January 18, 2019. https://bit.ly/2DslQY8?rel=0" . Accessed January 22, 2019.
  2. Ibrutinib Combined With Gemcitabine and Nab-Paclitaxel in Patients With Metastatic Pancreatic Cancer (144525). ClinicalTrials.gov website. clinicaltrials.gov/ct2/show/NCT02562898. Published September 29, 2015. Updated March 22, 2018. Accessed January 22, 2019.

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