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Immunotherapy, PARP Inhibitors Picking Up Steam in TNBC Pipeline

Chelsea LoCascio
Published: Monday, Oct 30, 2017

Howard A. “Skip” Burris, MD

Howard A. “Skip” Burris, MD
Ongoing clinical trials are exploring novel approaches in triple-negative breast cancer (TNBC), such as PARP inhibition and immunotherapy.

 
Early promise has already been observed, as phase Ib/II findings found that a combination of eribulin (Halaven) and pembrolizumab (Keytruda) was associated with an objective response rate (ORR) of 41.2% for untreated patients with metastatic TNBC.1

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