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Novel Combo Elicits Clinical Responses in Patients With "Cold" Melanomas

Jessica Hergert
Published: Wednesday, May 13, 2020

Adil Daud, MD, a clinical professor in the Department of Medicine (Hematology/Oncology), at the University of California, San Francisco and the director of Melanoma Clinical Research at the UCSF Helen Diller Family Comprehensive Cancer Center

Adil Daud, MD

Combining the PD-1 inhibitor pembrolizumab (Keytruda) with intratumoral plasmid interkeukin-12 (IL-12; tavokinogene telseplasmid; Tavo) electroporation elicited clinical responses in patients with immunologically quiescent advanced melanoma, according to results of a single-arm, phase 2 study (NCT02493361) published in Clinical Cancer Research.1
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