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Prolonging PFS With PARP Inhibitors in Platinum-Sensitive Ovarian Cancer

Caroline Seymour
Published: Thursday, Aug 22, 2019

Alexander Olawaiye, MD, director, Gynecologic Oncology Research Program, UPMCe

Alexander Olawaiye, MD

By blocking PARP, a key enzyme involved in DNA damage repair, investigators have been able to induce synthetic lethality, which in turn has led to dramatic clinical responses for patients with platinum-sensitive ovarian cancer.
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