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PSMA-Targeted Radionuclide Therapy Shows Preliminary Activity in mCRPC

Caroline Seymour
Published: Friday, Apr 10, 2020

Scott T. Tagawa, MD, MS, Richard A. Stratton Associate Professor in Hematology and Oncology

Scott T. Tagawa, MD, MS

The prostate-specific membrane antigen (PSMA)-targeted alpha-emitter 225actinium (225Ac) and radiolabeled monoclonal antibody J591 (225Ac-J591) showed encouraging preliminary safety and efficacy in men with pretreated, metastatic castration-resistant prostate cancer (mCRPC), according to findings from a phase I dose-escalation study (NCT03276572).
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