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Radium-223 Plus Anti-VEGF Therapy Reduces Bone Turnover in Advanced RCC

Published: Tuesday, Sep 26, 2017

The safety analysis included all 30 patients (15 in each group). The most common grade 3/4 adverse events with pazopanib were elevated liver-enzymes (ALT, 20%; AST, 14%), proteinuria, elevated serum amylase, and hypertension (13% each). In the sorafenib group, rash was most common (20%); grade 3/4 anemia, fatigue, serum amylase, hand-foot syndrome, and hypertension each occurred in 1 patient.

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