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Researcher Explores Biologic Basis for Disparities in Prostate Cancer Outcomes

Gina Columbus @ginacolumbusonc
Published: Thursday, Aug 25, 2016

Kosj Yamoah, MD

Kosj Yamoah, MD

A subset of biomarkers may predict the risk of clinicopathologic outcomes in an ethnicity-dependent manner, which may in turn explain ethnic disparities in prostate cancer outcomes between European and African-American men.



In an interview with OncLive during the 2016 OncLive State of Science Summit on Genitourinary Cancers, Kosj Yamoah, MD, a radiation oncologist at Moffit Cancer Center and lead author of the above-mentioned studies, discussed some of these health disparities in prostate cancer and unanswered questions researchers still need to tackle.

OncLive: What intrigues you about health disparities in prostate cancer?

Yamoah: I have been passionate about the disparities in prostate cancer. The data across the board show that African-American men or men of African descent have a 1.6-fold increase in incidence of prostate cancer and about a 2.4-fold increase in mortality in prostate cancer. When looking at those 2 numbers, we recognize that there are 2 questions that come up. Why are they getting prostate cancer more than the average population, and why are they actually dying from prostate cancer much more? Also, the age that they get prostate cancer is a slightly younger age.

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