Alessandro D. Santin, MD
Adding trastuzumab (Herceptin) to chemotherapy increased progression-free survival (PFS) for patients with advanced HER2/neu-positive uterine serous carcinoma, including those with recurrent disease and patients undergoing primary treatment.
Fader AN, Roque DM, Siegel E, et al. Randomized phase ii trial of carboplatin-paclitaxel versus carboplatin-paclitaxel-trastuzumab in uterine serous carcinomas that overexpress human epidermal growth factor receptor 2/neu [published online March 27, 2018]. J Clin Oncol. doi: 10.1200/JCO.2017.76.5966.
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