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Allie Strickler

Articles

AR Emerges as a Potential Target in Triple-Negative Breast Cancer

March 24th 2017

Whereas the androgen receptor (AR) is a common target in prostate cancer, emerging findings are showing a potential role for targeting AR in breast cancer, as well.

HER2 Gene Testing Guidelines May Misclassify Patients

March 13th 2017

Michael F. Press, MD, PhD, discusses issues with the ASCO-CAP guidelines on assessment of HER2 amplification by fluorescence in situ hybridization testing.

Expert Discusses Biomarkers for PARP Inhibitors in Ovarian Cancer

February 20th 2017

Dr. Elizabeth Swisher discusses biomarkers for PARP inhibitors and the evolving role of these agents in ovarian cancer.

Mirvetuximab Soravtansine Active in Platinum-Resistant Ovarian Cancer

February 17th 2017

Results of a phase I expansion study demonstrated a manageable safety profile and clinical activity with mirvetuximab soravtansine in the treatment of patients with platinum-resistant ovarian cancer.

Rovalpituzumab Tesirine Active and Safe in Small Cell Lung Cancer

February 13th 2017

Rovalpituzumab tesirine demonstrated encouraging single-agent antitumor activity with a manageable safety profile in the treatment of patients with recurrent small cell lung cancer.

Intentional Weight Loss Linked to Reduction in Endometrial Cancer Risk

February 10th 2017

Intentional weight loss in postmenopausal women has been found to be associated with a lower endometrial cancer risk, particularly among those with obesity, according to the results of a recent study published in the Journal of Clinical Oncology.

Disparities in Cervical Cancer Mortality Rates Highlight Need for Specialized Treatment

February 8th 2017

Anne Rositch, PhD, discusses important takeaways from her study on hysterectomy-corrected mortality rates in cervical cancer and the significance of cervical cancer screening.

Adding Antiandrogen Therapy to Radiation Improves Survival in Recurrent Prostate Cancer

February 6th 2017

The addition of hormonal therapy to radiation treatment following surgery significantly improved survival in patients with recurrent prostate cancer, according to the results of a study published in The New England Journal of Medicine.

Laparoscopy Plays Predictive Role for Primary Surgery Outcomes in Ovarian Cancer

January 28th 2017

Diagnostic laparoscopy reduced the number of futile laparotomies in patients with suspected advanced-stage ovarian cancer, according to the results of a recent study.

New Marker May Identify Men Who Require More Aggressive Prostate Cancer Treatment

January 27th 2017

A prostate-specific antigen nadir greater than 0.5 ng/mL following radiation and androgen deprivation therapy seems to identify men prior to PSA failure who are at high-risk for death, and would thus require more aggressive treatment for their prostate cancer.

Expert Discusses Updated HPV Vaccine Recommendations

January 26th 2017

Lois Ramondetta, MD, discusses the updated recommendations and the importance of advocating for lesser-known HPV-associated cancers.

Researchers Reveal New Subtype of Cervical Cancer

January 24th 2017

Carolyn E. Banister, MD, discusses the results of a study that uncovered a new subtype of cervical cancer, as well as some of the remaining challenges in the overall treatment landscape.

Prostate Cancer Treatment Rates Drop Following Changes in Screening Recommendations

January 19th 2017

A sharp decline has been observed in the overall rate of men receiving treatment for prostate cancer.

Expert Discusses Role of Vaginal Microbes in Endometrial Cancer Detection

January 19th 2017

A direct assessment of the uterine microbiome in patients with endometrial cancer has revealed a potential predictive role for vaginal microbes.

Watch-and-Wait Approach a Potential Option for Patients With Rectal Cancer

January 18th 2017

A watch-and-wait approach is emerging as a potential treatment strategy for patients with rectal cancer.

Novel Biomarker May Predict Recurrence in HPV+ Oropharyngeal Cancer

January 14th 2017

In the current treatment landscape of HPV-positive oropharyngeal squamous cell carcinoma, there is a significant lack of biomarkers to predict recurrence.

Early Endometrial Cancer Mutations Detectable in Uterine Lavage Fluid

January 14th 2017

As mortality rates continue to climb in endometrial cancer, there remains a pressing need for effective screening and diagnostics.

HER2 Vaccine Shows Promise in Early-Stage Breast Cancer

January 13th 2017

Anti-HER2 DC1 vaccination was demonstrated to be a safe and immunogenic treatment to induce tumor-specific T-cell responses in patients with HER2-positive breast cancer.

Herbst Discusses Next Steps With Pembrolizumab in Lung Cancer

January 11th 2017

Roy Herbst, MD, PhD, discusses the next steps with pembrolizumab in NSCLC, PD-L1 testing, and managing increased toxicities with combination regimens.

Expert Discusses Factors Associated With Local Control in Ewing Sarcoma

January 9th 2017

According to Dimosthenis Andreou, MD, patients with pelvic Ewing sarcoma have poorer local control and poorer overall survival.

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