Differentiated Thyroid Cancer: Unmet Needs and Future Directions
Experts highlight remaining unmet needs in the management of radioiodine-refractory differentiated thyroid cancer and share their hopes for the future.
Practical Advice for Community Endocrinologists and Oncologists Treating DTC
Before closing out their discussion on radioiodine-refractory DTC management, experts share practical advice for community physicians.
Patient Surveillance and Therapy Selection in RAIR DTC
Shared insight on active surveillance practices for patients with radioiodine-refractory DTC and how disease factors play into selection of therapy at time of recurrence.
Defining RAI-Refractory DTC and Selecting Patients for Disease Monitoring
Reflecting on a real-world patient scenario of DTC, experts consider how they identify radioiodine-refractory disease and when they would initiate systemic therapy.
Patient Profile 2: Diagnosing and Assessing DTC
Expert Lori Wirth, MD, highlights key points from a second real-world patient scenario of radioiodine-refractory differentiated thyroid cancer.
Treatment of DTC With Lenvatinib: Managing Adverse Events
Expert advice on addressing adverse events, particularly through dose holds or reduction, in patients on lenvatinib therapy for radioiodine-refractory DTC.
Optimizing the Use of Lenvatinib in DTC: Patient Selection and Dosing
Shared insight on selecting appropriate patients for lenvatinib therapy in differentiated thyroid cancer, as well as optimizing dosing strategies in the context of clinical trial data.
Role of Endocrinologists and Oncologists in the Management of DTC
A brief discussion on where endocrinologists and oncologists respectively fit into the differentiated thyroid cancer treatment paradigm.
Factors in Selecting Treatment for DTC
Reflecting on the first patient scenario of radioiodine-refractory DTC, experts share their considerations for optimally selecting and sequencing therapy in this setting.
Patient Profile 1: Lenvatinib in the Treatment of RAI-Refractory DTC
Perspectives on the use of lenvatinib therapy to manage a patient with radioiodine-refractory DTC, preceding broader considerations for sequencing kinase inhibitor therapy.
Patient Profile 1: Radioiodine-Refractory Differentiated Thyroid Cancer
Expert Marcia Brose, MD, details a clinical scenario wherein a patient is diagnosed with differentiated thyroid cancer and managed with surgical and radiotherapy.
T-DXd Demonstrates Real-World Efficacy in Advanced Breast Cancer With Dynamic HER2 Expression
Disparities in Survival Outcomes Revealed With BluePrint and MammaPrint Subtyping in HR+/HER2– Breast Cancer
Dr Freeman on Mortality Differences Across Racial Groups in Male Patients With Breast Cancer
Dr Parsons on the Correlation Between Liquid Biopsy and HER2 Status in Breast Cancer
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