SPOTLIGHT -
Looking Toward the Future Management of Non–Small Cell Lung Cancer
Closing out their discussion on non–small cell lung cancer, panelists share their expectations for future improvements in care.
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Non–Small Cell Lung Cancer: Targeted Agents for HER2, METExon14 and RET Alterations
Expert oncologists consider novel targeted agents in the setting of NSCLC with mutations in HER2, MET exon14, and RET, respectively.
Novel Therapy for NSCLC With ALK Rearrangements
Focusing on ALK-rearranged non–small cell lung cancer, expert panelists review data behind alectinib, brigatinib, and lorlatinib.
Novel Therapy for NSCLC With KRAS G12C Mutation
Expert perspectives on the management of KRAS G12C–mutant non–small cell lung cancer in the context of novel targeted agents.
Novel Therapy for NSCLC With EGFR Exon 20 Insertion Mutation
Panelists review the data behind treatment options for non–small cell lung cancer expressing EGFR exon 20 insertion mutation.
Is There a Role for IO Therapy in Advanced NSCLC With EGFR Mutations?
A brief review of suboptimal outcomes with immunotherapy in the setting of EGFR-mutant advanced non–small cell lung cancer.
Selecting Therapy for Advanced NSCLC With EGFR Mutations
Panelists review clinical trial data in the setting of EGFR-mutant advanced NSCLC and consider which therapy they would use at progression.
Neoadjuvant Strategies in Resectable Non–Small Cell Lung Cancer
Comprehensive review on various neoadjuvant strategies under review in the setting of resectable non–small cell lung cancer.
Adjuvant IO Therapy in Early-Stage NSCLC: The IMpower010 and PEARLS Trials
Expert perspectives on use of immunotherapy in the adjuvant setting of early-stage NSCLC in light of data from IMpower010 and PEARLS.
Adjuvant Osimertinib in Early-Stage NSCLC: The ADAURA Trial
Advances in Testing and Targeted Therapy for NSCLC: Translating Evidence to Clinical Practice
Selecting Appropriate Adjuvant Chemotherapy for Early-Stage NSCLC
Shared insight on the role and selection of adjuvant chemotherapy for patients with early-stage non–small cell lung cancer.
Treatment for Early-Stage NSCLC: Resection and Adjuvant Radiation Therapy
Shifting focus to early-stage NSCLC, expert panelists define the role of resection and consider when it is appropriate to utilize adjuvant radiation therapy.
Molecular Testing in Advanced-Stage NSCLC: Use of Liquid Biopsy
Expert oncologists briefly highlight the role of liquid biopsy in the setting of advanced-stage non–small cell lung cancer.
Use of Molecular Profiling in Early-Stage Non–Small Cell Lung Cancer
A focused discussion on the use of molecular profiling in early-stage non–small cell lung cancer to inform decisions on adjuvant and neoadjuvant strategies.
Real-World Data and Barriers to Use of Molecular Testing in NSCLC
A brief review of real-world data behind molecular profiling in non–small cell lung cancer, followed by a discussion on barriers to testing and uptake.
Optimal Molecular Testing Practices in Non–Small Cell Lung Cancer
Expert panelists share insight on molecular testing practices across all subtypes of non–small cell lung cancer to optimally inform treatment decisions.
Dr. Donington on the Role of Neoadjuvant Immunotherapy in Stage II NSCLC
Jessica Donington, MD, MSCR, discusses the role of neoadjuvant immunotherapy in patients with stage II non–small cell lung cancer.
Dr. Donington on Neoadjuvant Immunotherapy in Lung Cancer
Jessica Donington, MD, MSCR, discusses the effectiveness of neoadjuvant immunotherapy and how it compares with neoadjuvant chemotherapy in patients with lung cancer.
Darolutamide Demonstrates Activity, Safety in AR-Positive Salivary Gland Cancer
Lenvatinib Plus Pembrolizumab Maintains Survival Benefit in Advanced ccRCC
Enfortumab Vedotin Plus Pembrolizumab Produces Durable Responses, Safety in Metastatic Urothelial Carcinoma
Cabozantinib Plus Nivolumab/Ipilimumab Generates PFS and DCR in Metastatic Soft Tissue Sarcoma