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Opinion|Videos|May 7, 2025

Enhancing Early-Stage NSCLC Diagnosis: Leveraging Pathology and Imaging for Accurate Staging

Panelists discuss how a multidisciplinary team—including oncologists, thoracic surgeons, radiologists, and pathologists—collaborates to streamline the diagnostic process for patients with resectable non–small cell lung cancer (NSCLC), ensuring timely evaluation, accurate staging, and personalized treatment planning.

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Multidisciplinary Team Approach to Resectable NSCLC Diagnosis

The multidisciplinary team (MDT) plays a crucial role in ensuring an efficient and accurate diagnostic process for patients with resectable NSCLC. Each team member contributes specialized expertise to optimize patient care:

  • Thoracic Surgeon: Evaluates surgical candidacy, determines resectability, and collaborates on treatment planning
  • Medical Oncologist: Assesses the need for neoadjuvant or adjuvant systemic therapy and coordinates with other specialists for comprehensive care
  • Radiation Oncologist: Provides input on the role of radiation therapy in borderline resectable cases or as an adjunct to treatment
  • Pulmonologist: Conducts bronchoscopy, tissue biopsy, and pulmonary function assessments to aid in diagnosis and surgical planning
  • Radiologist: Interprets imaging studies (CT, PET, MRI) to assess tumor stage and resectability
  • Pathologist: Analyzes biopsy specimens to confirm histologic diagnosis and identify molecular markers guiding therapy
  • Nurse Navigator/Coordinator: Ensures seamless communication between specialties, facilitates timely scheduling, and supports patient education

The MDT collaborates through regular case discussions, integrating imaging, pathology, and clinical findings to determine the optimal diagnostic and treatment strategy. This coordinated approach minimizes delays, enhances decision-making, and improves patient outcomes.

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