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Mike Hennessy

Articles by Mike Hennessy

The search for biomarkers that can help clinicians match patients with effective therapies continues at a torrid pace in oncology. Yet in the parlance of basketball, not all biomarkers translate into slam dunks when it comes to clinical utility.

Although there often is controversy over the impact of new cancer drugs on patients’ overall survival, there can be little argument over the broad improvements that have flowed from more than four decades of investment in oncology research.

There are many reasons, why we must now move beyond the "one drug-one test" model that has resulted in these diagnostics.

Moving the Meter

Although the progress made in the treatment of patients with lung cancer has by now become a familiar story, it certainly bears repeating.

For oncology specialists, caring for patients with cancer has long meant analyzing the biological and clinical pieces of a puzzle unique to each individual and then figuring out the optimal management plan to meet his or her needs.

With two drugs on the market and more agents in the pipeline, there's little doubt that immunotherapies targeting the PD-1/PD-L1 pathway will become a backbone of oncology treatment in the near future, perhaps replacing chemotherapy in some malignancies.

The rise of electronic medical reporting and value-based standards and measures for improved medical care is supported by the best of intentions, but the implication is that physicians now spend more time behind the computer terminal and less time with patients.

One of the most gratifying aspects of working in the oncology information field is the opportunity we have to interact with the scientists and clinicians who are seeking to advance the care of patients with cancer.

The road to becoming the first biosimilar to go on sale in the United States has been uneven for Zarxio (filgrastim-sndz), a Sandoz product for raising white blood cell counts.

During the past five years, the progress in therapeutic options for men with prostate cancer has been truly remarkable.

Competitive pressures and profound marketplace changes are a fact of life for the oncology business, and for a practice in San Antonio, Texas, that handles a large population of rural poor, planning sessions routinely involve discussions on how to stay independent and continue doing things the way physicians there feel is best.

Given the higher risk of breast and ovarian cancer in BRCA mutation carriers, should broader screening for the abnormality be implemented?

The rise of high-deductible health plans has been accelerated by the Affordable Care Act, yet for many oncology practices this trend adds to the administrative workload and creates deep uncertainty on the accounts receivable side.

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